Recognition of chiral anions using calix[4]arene-based ureido receptor in the 1,3-alternate conformation
2014
Abstract
A new type of calixarene-based receptor designed for the recognition of chiral anions was prepared by the introduction of (S)-2-methylbutan-l-ol moieties into the lower rim of calixarene. The immobilization of calixarene skeleton in the 1,3-alternate conformation enabled the construction of a cavity consisting of preorganised ureido functions and chiral substituents in close proximity.
This cavity is capable of chiral discrimination of selected anions as demonstrated on D- and L-phenylalaninates.