Monepantel (MOP), a new anthelmintic drug from group of amino-acetonitrile derivatives, has been intensively studied during last years. Many authors examined this new drug from different perspectives, e.g. efficacy against different species and stages of parasites, mode of action, metabolism, pharmacokinetics, toxicity, resistance, ecotoxicity etc.
The aim of presented review was not to collect all reported data but to bring an overview of various approaches in the study of MOP and to evaluate their principle results.