Abstract
Systemic sclerosis / sclerosis (SSc) is an autoimmune a disease characterized by microvascular, fibrosis of skin and visceral organs and disorders of humoral and cellular immunity. The characteristic part of the picture this disease is vascular pathology - fibrotic sclerotisation of medium and small arteries and capillaries, which results in prolonged attack of Raynaud's phenomenon.
In more advanced stages of this vasoneuroses trophic changes on acres could be observed, including digital ulcers (DU), necrosis and gangrene of the fingers. DU is one of the main causes of disability in patients with SSc.