Abstract
Erectile dysfunction can be an early clinical marker for the presence of endothelial dysfunction, systemic vascular abnormalities including coronary artery disease. Erecitle dysfunction is a predictor of a serous cardiovasculat event in men aged 30-60 years and in diabetics, the time interval is 2-5 years.
Erectile dysfunction is highly prevalent in type two diabetes mellitus in 75%. Erectile dysfunction is associated with oncological diseases - colorectal and prostate carcinoma.
Spinal cord injury and pelvic injury are associated with neurogenic erectile dysfunction. The moden oral therapy for erectile dysfunction therapy using PDE5 inhibitors and intracavernosal therapy using Alprostadil is safe, effective and is well tolerated.
Oral or intracavernosal penile rehabilitation therapy is indicated especially in oncological patients in prevention of irreversible damage of cavernosa tissue.