In the group of our 6 patients in the study with afatinib we observed typically adverse events associated with treatment with tyrosine kinase inhibitors. It is a diarrhoea, rash and paronychia.
These complications do not affect the comfort of the patients seriously. Other side effects that could be associated with the treatment were transient swelling, epistaxis and conjunctivitis.
Treatment with afatinib in our group of patients is very well tolerated.