Decreased Circulating Visfatin Is Associated with Improved Disease Activity in Early Rheumatoid Arthritis: Data from the PERAC Cohort

Abstract

In this study we found that serum visfatin was significantly elevated in early RA patients compared to healthy controls and significantly decreased after three months of treatment. Circulating visfatin and a change in visfatin level correlated with disease activity and improved disease activity over time.

Furthermore, a decrease in visfatin after three months predicted disease activity improvement after 12 months

Keywords

• Rheumatoid arthritis
• disease activity
• visfatin