Publication at Central Library of Charles University, Second Faculty of Medicine, Faculty of Medicine in Hradec Králové |
2015
Abstract
Stem cells biology is one of the most frequent topic of physiological research of today. Spinal fusion represents common bone biology challenge.
It is the indicator of osteoinduction and new bone formation on ectopic model. The purpose of this study was to establish a simple model of spinal fusion based on a rat model including verification of the possible use of titanium microplates with hydroxyapatite scaffold combined with human bone marrowderived mesenchymal stem cells (hBMSC's).