Paracetamol poisonings in the Czech and Slovak Republic and N-acetylcysteine treatment. Data analysis
2014
Abstract
Paracetamol overdose belongs to frequent calls to Toxicological Information Centre (TIC) in the Czech Republic and to the National Toxicological Information Centre (NTIC) in Slovakia. The aim of the study was to evaluate outcomes and side effects of paracetamol overdose in both countries.
Our data support the opinion that NAC should not be used in patients with <149 mg/l levels in absence of higher risk factors because of very low risk of hepatotoxicity on one side, and side effects on the other side.