Serum sclerostin in high-activity adult patients with juvenile idiopathic arthritis

Abstract

A significant correlation between the sclerostin serum concentration and the number of tender and swollen joints, but not BMD, supports the hypothesis that chondrocytes and cells of the subchondral bone may contribute to circulating sclerostin in juvenile idiopathic arthritis.

Keywords

• Juvenile idiopathic arthritis
• bone mass density
• anti-TNFα treatment
• DAS 28
• hsCRP
• sclerostin
• Dkk1