Publication at Faculty of Physical Education and Sport, First Faculty of Medicine |
2014
Abstract
We evaluated the expression of podoplanin in α-smooth muscle actin positive myofibroblasts producing the suburothelial layer in tunica propria of the urinary bladder that have some similar features with telocytes. We observed positive reaction not only in bioptic specimens from women with interstitial cystitis, but also in a control group of women and men treated for pathological bladder lesion different from intersititial cystitis.
Our findings suggest that D2-40 can be used as a complementary immunostainer to α-smooth muscle actin on urinary bladder biopsies from patients with interstitial cystitis.