Abstract
Many syndromes (e.g. Hajdu-Cheney, Ehlers-Danlos, Axenfeld-Rieger) are joint together with different affection on dentition, interjaw relations, cleft disorders, early loss of teeth, hypoplastic jaws, alveolar bone loss with consequent influence on the whole masticatory functions.
Dentists may become the first diagnosticians, who express primary suspicion on born abnormality based on disorders of masticatory system.