Publication at First Faculty of Medicine |
2014
Abstract
Gestodene is a derivative of 19-nortestosterone and gonan with no residual androgenic activity. It belongs to the 3rd generation of progestins.
Monophasic combination of 20 μg EE and 75 μg GSD has been clinically proven contraceptive with high efficiency and high compliance of patients. In trials it has been shown its metabolic neutrality, minimal risk in body weight changes, no blood pressure changes, sufficient anti-androgenic effect and good control of pseudomenstruation cycle.