Abstract
Beginning of pollen season brings us each year an increasing amount of patients suffering from allergic rhinoconjunctivitis. It has been estimated that in Czech Republic 2.5 millions people suffer from any kind of allergic disease and about 15 % suffer from allergic rhinitis.
Etiopathogenesis of allergic rhinitis is based on IgE - mediated response of organism onto frequent contact with an allergen. Eosinophilic inflammation is then the final result of this activation and leads to clinical symptoms as a runny nose, obturation, sneezing and fatigue.
Suppression of the inflammation is the first-line task. Symptomatic therapy represents mostly using of antihistamines in systemic and local application and nasal corticosteroids.
In indicating cases we use specific allergen immunotherapy which is potentially a causal therapy.