Abstract
Individual asthma phenotypes are characterized by a different of bronchial inflammation and present with distinct clinical features, a different response to anti-inflammatory pharmacotherapy, and a different course and prognosis. The combination of current classification (severity, type of mucosal inflammation, and control achievement) provides a relatively precise presentation of the disease and prognosis in an asthma sufferer.
The diagnosis includes the degree of breathing disorder, reversibility of bronchial obstruction, exhaled nitric oxide testing prior to treatment (or during its course), and triggers of asthma attacks. The diagnosis is supplemented by complicating comorbidities.
This is not a definitive text, but a dynamic description of the disease. Bronchomotor tests linked to FeNO testing have separated a group of patients that exhibit symptoms of both asthma and chronic obstructive pulmonary disease.
Hence, the term "overlap syndrome" (an overlap of COPD genotype with asthma) or the acronym ACOS (asthma-chronic obstructive pulmonary disease overlap syndrome) are encountered.