Publication at First Faculty of Medicine |
2014
Abstract
Systemic lupus erythematosus (SLE) is a chronic inflammatory disease characterized by varied clinical findings and positivity of autoantibodies. In some patients, the autoantibodies typical for SLE are present, but the clinical symptoms of the disease are absent.
Conversely, other patients may have the typical clinical symptoms of SLE, but antinuclear antibodies are absent. Only regular follow-up of individual clinical and immunological signs of the disease enables an early determination of the diagnosis and subsequent initiation of therapy.