The introduction of highly-sensitive method for the assessment of cardiac troponins represents a progress in diagnostics, therapy and risk stratification in acute coronary syndromes. It provides earlier diagnosis and increase of the sensitivity in the diagnostic process of acute myocardial infarction.
Further increase of the sensitivity can be achieved with simultaneous assessment of other markers (copeptin, heart fatty acid binding protein) or evaluation of additional clinical parameters (electrocardiogram, GRACE or TIMI risk score). The question of the rule-out protocols remains opened in the process of evaluation of the coronary etiology of chest pain.