Publication at Central Library of Charles University |
2013
Abstract
Exploration of 9-bromo[7]helicene reactivity mainly in Pd-catalyzed reactions is reported. Palladium catalyzed carbonecarbon and carboneheteroatom coupling reactions provide a large portfolio of racemic helicenes bearing different functional groups in good to excellent yields.
Many of the reactions were performed in the microwave reactor keeping reaction time to a minimum compared with conventional synthetic methods.