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Examination of cardiovascular reactivity in patients with hereditary neuropathy

Publication at Second Faculty of Medicine |
2014

Abstract

The hereditary motor and sensitive neuropathy, morbus Charcot Marie Tooth, is one of the most common neuromuscular diseases in the world. In recent years a proofs suggesting, that illness has an autonomic component were found.

On a group of 17 patients suffering from Charcot Marie Tooth disease we executed a study focused on the examination of autonomic nervous system. For the most of patients, the symptoms of autonomic neuropathy were proved.

Some of examined patients described subjective problems, especially gastrointestinal and sudomotor troubles. The autonomic neuropathy is also risk factor of cardiovascular morbidity, which is in relation with motor handicap and common deconditioning of patients with neuropathy important factor in deteriorating quality of life and health.