Probiotics are topic of interest of clinical as well industry researchers, because of their biological and economical potential. Nasal application in the world letters was not published yet.
Safety L. acidophilus CCD151 a L. helveticus CCGM 98 mixture was tested in adults and than used in children in the initial phase of a nasal, nasopharyngeal infection. In the set of 76 children using lactoflora solution intranasally in 8.1 % was necessary use antibiotics in the further treatment, in the control set of 31 children in 22 %.
There were no serious adverse reactions.