Publication at Faculty of Medicine in Pilsen |
2015
Abstract
Vismodegib is a low-molecular inhibitor of hedge-hog signalinf pathway that regulates cell growth. Its activation in adults leads to formation of some tumours, especially, basal cell carcinoma.
Authors describe a case of 75-year old patient with unsuccessfully treated advanced, recurrent and inoperable basal cell carcinoma. The tumour healed after six months treatment with vismodegib.