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Microvascular density in lymphomas - evaluation methods and clinical impact

Publication at Faculty of Medicine in Pilsen |
2015

Abstract

In recent years antiangiogenic therapy has become a part of treatment rotocols of solid tumors as well as of lymphomas. This i why tumor vascularization has been expored, the most important parameters to describe it being the microvascular density and immunohistochemical assessment of the expression of VEGF (vascular endothelial growth factor) and of its receptors. this review summarizes various methods of assessment of the microvascular density and the prognostic impact of microvascular density in lymphomas.