Publication at Second Faculty of Medicine |
2015
Abstract
Probiotics have become very popular over the last two decades for the ability to influence intestinal microbiota composition and to alter host epithelial and immunological responses. Certain probiotic interventions have shown promise in selected clinical conditions where aberrant microbiota have been reported, such as acute infectious diarrhea, necrotising enterocolitis, irritable bowel syndrome and prevention of atopic dermatitis.
Conclusions are based on meta-analyses of double-blinded, placebo-controlled studies which can only demonstrate the efficacy of probiotics in prevention and treatment of certain diseases.