Heteroatom-substituted tetra(3,4-pyrido)porphyrazines: a stride toward near-infrared-absorbing macrocycles

Abstract

A synthesis procedure for heteroatom-substituted tetra(3,4-pyrido)porphyrazines that absorb light near 800 nm was developed. Based on the observed relationships between the structure and photophysical parameters, a novel highly photodynamically active (IC50 = 0.26 mu M) compound was synthesized and biologically characterized.

Keywords

• photophysical properties
• peripheral substituents
• key role
• phthalocyanines
• azaphthalocyanines
• electrochemistry
• fluorescence
• derivatives
• absorption
• complexes