Publikace na Přírodovědecká fakulta |
2015
Abstrakt
Cross-metathesis of alpha -and beta-vinyl C-deoxyribosides and alpha-vinyl C-galactoside with various terminal alkenes under different conditions was studied. The cross-metathesis of the former proceeded with good yields of the corresponding products in ClCH2CH2Cl the latter required the presence of CuI in CH2Cl2 to achieve good yields of the products.
A simple method for the preparation of alpha- and beta-vinyl C-deoxyribosides was also developed. In addition, feasibility of deprotection and further transformations were briefly explored.