Abstract
Alzheimer's disease (AD) is one of the plagues of modern era. Increasing mean age of a population in combination with the overall high prevalence and incidence of AD in elderly population and very high both direct and indirect health care costs of the disease, makes AD one of the most expensive diagnosis in the developed countries.
Vaccination is one of the best cost effective approaches of the therapeutic interventions. Progresses in immunotherapeutic approaches in AD therapy are watched with great anticipations both by healthcare professionals and general population.
In this review we would like to summarize up-to date immunotherapeutic approaches in clinical development and to present current research trends that could lead to the breakthrough in AD therapy or prevention.