Abstract
Bipolar affective disorder is associated with an impairment of cognitive functions. Contemporary data do not provide sufficient evidence to describe such impairment as progressive or stable.
Our aim was to explore the course of cognitive functions development in one-year longitudinal study. The second aim was to further scrutiny for possible connection of cognitive functions alteration and change in cardiometabolic risk factors prevalence.
We have found an improvement in cognitive performance and favorable change in atherogenic index during the one-year longitudinal study. Progressive nature of cognitive impairment was not observed.
The detection of cognitive improvement in the same time as favorable atherogenic index change suggests the possibility of enhancing cognition by the treatment of cardiometabolic risk factors.