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Detection of intraamniotic inflammation in fresh and processed amniotic fluid samples with the interleukin-6 point of care test

Publication at Faculty of Medicine in Hradec Králové |
2015

Abstract

The main objective of this paper was to test whether the amniotic fluid interleukin-6 point of care cut-off of 745 pg/mL could be used for the identification of intraamniotic inflammation in fresh, noncentrifuged amniotic fluid from pregnancies complicated by preterm prelabor rupture of membranes. A strong correlation between the amniotic fluid interleukin-6 concentrations in the fresh and processed samples was found.

Therefore, an interleukin-6 concentration of 745 pg/mL measured by the point of care test could be used as the cut-off to identify intraamniotic inflammation in cases in which fresh, noncentrifuged amniotic fluid is used.