Abstract
Lipids play a significant role in the physiology of the body as part of energy reserves, are precursors of the hormones in the cell membrane, their derivatives participating in signal transduction. Lipid metabolism and its disorders are related to a number of important diseases (atherosclerosis and its complications, type 2 diabetes mellitus, chronic kidney disease and liver), but also play an important role in neuropsychiatric diseases such as schizophrenia, affective disorders, dementia and other.
Disorders of lipid metabolism, present in neuropsychiatric disorders are also involved in the pathogenesis of comorbidities that are patients with these diseases associated with increased mortality and overall survival time shortening. The drugs used in the treatment of disorders of lipid metabolism can interfere in different ways in the pathogenesis of neuropsychiatric diseases.
This article discusses the relationship of lipids to pathogenesis neuropsychiatric most serious illnesses, such as schizophrenia, depression and Alzheimer's disease.