Abstrakt
Background: Wilms' tumor gene 1 (WT1) is a transcription factor essential for normal development of the urogenital system and male gonadal formation. Its alterations have been found in Wilms' tumor, other malignancies and testicular dysgenesis syndromes.
We studied WT1 aberrations to address its role in the pathogenesis of testicular germ cell tumors (TGCT).