Prognostic value of anti-CRP antibodies in lupus nephritis in long-term follow-up

Abstract

Autoantibodies against monomeric C-reactive protein (anti-CRP-Ab) observed in patients with systemic lupus erythematosus (SLE) and lupus nephritis (LN) were suggested to be associated with active LN and a poor response to therapy during short-term follow-up. The aim of this study was to confirm this finding and to investigate the prognostic value of anti-CRP-Ab in patients with LN during long-term follow-up.

Keywords

• c-reactive protein
• disease-activity
• sjogrens-syndrome
• interferon-alpha
• immune deposits
• serum-levels
• erythematosus
• autoantibodies
• glomerulonephritis
• classification