En bloc resection of urothelium carcinoma of the bladder (EBRUC): a European multicenter study to compare safety, efficacy, and outcome of laser and electrical en bloc transurethral resection of bladder tumor
Abstrakt
En bloc resection of bladder tumors (ERBT) may improve staging quality and perioperative morbidity and influence tumor recurrence. This study was designed to evaluate the safety, efficacy, and recurrence rates of electrical versus laser en bloc resection of bladder tumors.
This European multicenter study included 221 patients at six academic hospitals. Transurethral ERBT was performed with monopolar/bipolar current or holmium/thulium laser energy.
Staging quality measured by detrusor muscle involvement, various perioperative parameters, and 12-month follow-up data was analyzed. Electrical and laser ERBT were used to treat 156 and 65 patients, respectively.
Median tumor size was 2.1 cm; largest tumor was 5 cm. Detrusor muscle was present in 97.3 %.
A switch to conventional TURBT was significantly more frequent in the electrical ERBT group (26.3 vs. 1.5 %, p 1 cm. Recurrence rates did not differ between groups, and the majority of recurrences occurred outside the ERBT resection field.