Abstrakt
We report two cases of water intoxication in adolescents. In case 1, an 18-year-old boy with mild mental retardation 5 months after cadaveric kidney transplantation due to bilateral kidney hypoplasia presented with hyponatraemic seizures and a sodium level of 119 mmol/L.
He was normotensive at the time of the convulsions. His diuretic treatment was significantly reduced the day before the occurrence of the seizure because of high urine output.
The dosage of furosemide was reduced from 200 to 120 mg/day, and hydrochlorothiazide (75 mg/day) was suspended. He was instructed to lower oral intake proportionately, but he drank 2.5 L of water in 2 h, which caused dilutional hyponatraemia.
The patient was treated with hypertonic saline, and his serum sodium normalized within 36 h.