Monoclonal antibodies in the treatment of dyslipidemia and cardiovascular risk reduction

Abstract

Proprotein-substilisin kexin convertase 9, PCSK9, is a protease which binds to LDL-receptor protein and thus impacts significantly on the resulting levels of LDL-cholesterol in the plasma.

Keywords

• Cardiovascular risk
• LDL-cholesterol
• lipid lowering drugs