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Metal intolerance in patients undergoing orthopedic implant therapy

Publikace

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

Implants are widespread used mainly as orthopedic and dental implants. Although the majority of implants is well accepted, significant minority of implants is not accepted from unclear reasons.

In patients in whom other causes of implant failure were excluded it is therefore appropriate to determine if they tolerate the material from which their implant is made. For evaluation of metal intolerance the Melisa test was used.

Aim of the study: To minimize the risk of implantation failure after orthopedic surgery in patients after not exactly successful implantation therapy with need of reimplantation or in patients with increased risk of implantation failure due to polyvalent allergy. Material and methods: Thirty-eight patients were examined.

In concordance with Helsinki declaration and after signature of informed consent every examined patient underwent blood sample collection for Melisa test performance. Results: In this group of patients, intolerance to nickel was the most common (55%).

Intolerance to gold was found in 52% of patients, to paladium and chromium in more then 40% of patients, to titanium trichloride in 38% of patients, to iron in 29% of patients, to molybden mand titanium dioxide in 27% of patients, to cobalt in 23% of patients and to zirkonia in 19% of patients. Few case studies will be presented.

Conclusion: On the basis of immunologic examination results more suitable implant material from available materials regarding to individual susceptibility of the patient was selected for reimplantation.