Current options of chemoradiotherapy treatment in locally advanced rectal carcinoma

Abstract

The standard treatment of locally advanced rectal carcinoma is neoadjuvant chemotherapy followed by total mesorectal excision. Neoadjuvant chemoradiotherapy has demostrated lower incidence of local recurrence and better profile of toxicity then adjuvant chemoradiotherapy.

The next article presents current view on treatment options, controversial issues and used the targeted treatment in locally advanced rectal carcinoma.

Keywords

• rectal carcinoma
• radiotherapy
• chemotherapy
• targeted treatment