Publikace na 1. lékařská fakulta |
2016
Abstrakt
According to recent reported findings, stress experiences are related to neurobiological processes that may have lasting consequences and significantly influence brain functions. These stress experiences may lead to cognitive and emotional dysregulation related to deficits in inhibitory functions and increased limbic excitability that may cause temporo-limbic seizure-like activity and specific changes in neural dynamics and complexity of neural networks.
These findings indicate that stress-activated limbic kindling may be involved in the pathogenesis of post-traumatic stress disorder and some other psychiatric disorders which may explain the efficacy of antiepileptic drugs.