The DAPT trial: 12 or 30 months of dual antiplatelet therapy after implantation of drug-eluting stent

Abstract

The DAPT trial investigated the prolongation of dual antiplatelet therapy after drug-eluting stent implantation to 30 months. Almost 10,000 patients were randomized to either prolonged therapy or standard therapy of 12 months.

This resulted in a decrease in ischaemic events and an increase in bleeding events in the arm with prolonged duration of therapy.

Keywords

• dual antiplatelet therapy
• drug-eluting stent
• aspirin
• clopidogrel
• prasugrel
• ticagrelor