Reinvestigation of acetylation of 3,4-dihydroxybenzaldehyde and reconciliation of previously reported analytical data

Abstract

Acetylation of 3,4-dihydroxybenzaldehyde was reinvestigated. The results in the regiochemical outcome were analyzed in detail by NMR methods and compared with previously published data.

Keywords

• Acylation
• Regioselectivity
• Rearrangement
• NMR spectroscopy
• Methanolysis