The official guidelines of the Czech Gastroenterology Society cover all aspects of biological therapy of inflammatory bowel disease. The Guidelines are divided into following sections:
1) introduction;
2) indication of biologics in Crohn's disease (infliximab, adalimumab, vedolizumab);
3) indication of biologics in ulcerative colitis (infliximab, adalimumab, golimumab, vedolizumab);
4) contraindications of biological therapy;
5) screening investigations;
6) administration of biologics;
7) termination of biological therapy; 8; pregnancy, lactation and vaccinations of newborn children;
8) prophylaxis and therapy of allergy to infliximab;
9) side effects of biologics;
10) biosimilars;
11) monitoring of patients during administration.