Publication at First Faculty of Medicine |
2016
Abstract
The majority of patiens with Crohn's disease require surgery during the course oftheir disease. But surgery is not curative.
Majority of patients develop disease reccurence at or above the anastomosis. Reccurence disease is characterized new lesions.
Factors predisposing to reccurence are not well defined. Prevention of recurrence after intestinal resection is a major goal in Crohn's disease therapy.
A majority of patiens receive a prophylactic therapy with thiopurine and anti-TNFalfa.