Hidradenoma papilliferum: a clinicopathologic study of 264 tumors from 261 patients, with emphasis on mammary-type alterations
Abstrakt
Hidradenoma papilliferum (HP), also known as apillary hidradenoma, is the most common benign lesion of the emale anogenital area derived from anogenital mammary-like lands (AGMLG). HP can be viewed conceptually as the utaneous counterpart of mammary intraductal papilloma.
The uthors have studied 264 cases of HP, detailing various changes in he tumor and adjacent AGMLG, with emphasis on mammarytype lterations. In many HP, the authors noticed changes typical for benign breast lesions, such as sclerosing adenosis-like changes, usual, and atypical ductal hyperplasia.
Almost in a third of cases, remnants of AGMLG adjacent to the lesion were evident, manifesting columnar changes reminiscent of those seen in breast lesions. This study shows that the histopathological changes in HP run a broad spectrum comparable with that in the mammary counterpart and benign breast disease.