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How to assess high-sensitive troponin T in newborns?

Publication at Faculty of Medicine in Pilsen |
2016

Abstract

In the prospective study cord blood samples were tested for high-sensitivity troponin T reference concentration in 454 healthy full termed newborns. The hscTnT levels in healthy newborns were significantly higher than levels in adult population (median [IQR] 38.2 [31.3-48.0] ng/ l reference interval: 20.1-83.0 ng/ I).

We found statistically higher hscTnT in boys when compared to girls (p=0.05). Concentrations of hscTnT were lower in newborns who underwent cesarean section than delivered vaginally (p=0.008).

Furthermore, hscTnT was statistically significantly decreased in hemolytic blood samples (hemolysis level >2g/I, p<0.05). Identified reference values of hscTnT based on this study may contribute to more precise assessment of newborns with suspicion of a myocardial disorder.