Bioresorbable vascular scaffolds in STEMI patients: multimodality imaging comparison in mid-term perspective
Abstract
Bioresorbable vascular scaffolds (BVS) represent an exciting and novel coronary intervention technology. BVS implantation could play an important role in the acute ST elevation myocardial infarction (STEMI) setting, with mid- and long- term follow-up data still scarce.
PRAGUE-19 is a prospective double-center single arm study that tests the performance and safety of BVS implantation during primary percutaneous coronary intervention (pPCI) in the STEMI setting. During the enrollment period 70 patients were included, quantitative coronary angiography (QCA) was done immediately after BVS implantation and optical coherence tomography (OCT) study was suggested but not mandatory; subsequently serial clinical follow-up was scheduled and research computed tomography (CT) angiography at 1 year was performed.
Current work focuses on a group of 22 patients who had complete multi- imaging data (QCA and OCT immediately post-procedure and CT at 1 year after implantation) available and aims to analyze the quantitative measurements of these different techniques. In comparison with OCT, QCA largely underestimates luminal diameters and may interfere with BVS proper sizing.
CT angiography did not identify any evidence of binary restenosis confirming the effective anti-restenotic properties of BVS at mid-term follow-up. Our multimodality imaging approach did not demonstrate any significant reduction of the percent stenosis area at 1 year after implantation.