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Ganglion cell complex depending on the intraocular pressure

Publication at First Faculty of Medicine, Faculty of Medicine in Hradec Králové |
2016

Abstract

Abstract Objective: The aim of the study was to determine whether high intraocular pressure (IOP) affects the GCC thickness. Patients and methods of examination: Patients were divided into two groups.

The first control group included eight women (from 25 to 65 years) and two men (25 and 59 years). The second group consisted of six women (from 30 to 75 years) and four men (from 30 to 58 years).

This was a group of patients who were diagnosed with high intraocular pressure (IOP), either as a first detection of glaucoma or after cataract surgery, or as a manifestation of poorly controlled glaucoma. All patients had their IOP monitored both before and after its compensation.

Further, the average thickness of the ganglion cell complex (GCC) (using the SD-OCT RTvue-100) and the visual field (using the fast threshold program of Medmont M 700 device) were measured before and one month after IOP compensation. The first group was also measured after the additional interval of one month.

Results: The correlation between the value of intraocular pressure and GCC before and after the compensation was evaluated. The resulting correlation coefficient was r = - 0.0297, p = 0.9010 in the control group and r = - 0.03, p = 0.9328 in the second group with high intraocular pressure.

Dependence in both groups was negligible and statistically insignificant. Conclusion: Although, at first glance, the GCC values appear to be increased after the correction of IOP, statistically significant changes in the thickness of the GCC were not recorded.