Introduction: Prehepatic portal hypertension (PH) in the absence of cirrhosis and solid tumours is most commonly caused by thrombosis of the portal vein (PT). Thrombosis in the portal system manifests as either acute abdominal pain or occurs silently, and varices develop in response to increased portal blood pressure.
In 2016, the European Association for the Study of the Liver issued a new clinical practical guideline for the treatment of PT. To treat acute PT, it is advised that anticoagulation therapy is initiated immediately.
It is recommended to treat patients with chronic PT by the same way as patients with PH caused by liver cirrhosis. Aim: The aim of this study was to describe a group of patients with portal thrombosis at the University Hospital in Hradec Kralove (FNHK) and to compare the therapeutic approaches used with those of the new guidelines.