Metabolic syndrome in patients with diabetes mellitus type 1, prevalence, impact on morbidity and mortality

Abstract

Aim of this retrospective observational study was to determine the prevalence of metabolic syndrome (MS) in patients with diabetes mellitus type 1 (DM1Z) at baseline (in 2003) and find the parameters that determine the difference between group with (MS+) and without MS (MS-). Did the presence of MS affect morbidity and mortality in the subsequent 10 years? 278 patients were enrolled to the study with age average 39 +- 13 years with medical history of diabetes 15.9 +- 9 years.

The IDF criteria were used for MS diagnosis. Anthropometric and biochemical parameters, prevalence and incidence of microangiopathic and macroangiopathic complications were checkedat baseline and after 10 years.

Keywords

• cardiovascular diseases
• diabetes mellitus type 1
• insulin distance
• metabolic syndrome
• microvascular complications
• mortality