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Inactivation of dermatophyte infection by nonthermal plasma on animal model

Publikace na 1. lékařská fakulta, Lékařská fakulta v Hradci Králové |
2017

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

We attempted to verify the artificial infection of the guinea pigs skin caused by dermatophyte Trichophyton mentagrophytes SK 3286 may be improved and shortened by exposure to low-temperature plasma produced by the direct current cometary discharge with inserted grid. The electrodes are arranged at an angle of 30o, their tips are 5-7 mm apart and the tip of the positive electrode.

Under the current between 50-100 μA, the discharge resembling a comet's tail appears between the electrodes. Experimental study was performed in guinea pigs strain Dunkin Hartley, both sex.

It was verified that exposure to the low-temperature plasma causes no damage to experimental animals. The dermatophytic infection was a week shorter and milder in animals treated by plasma than that in non-treated animals.

The significant lowering of dermatophytic germs also occurred in the treated group. These results give a chance for the elaboration of a scheme for the therapy of dermatophytosis by low-temperature plasma treatment.