Clinical improvement and reduction in serum calprotectin levels after an intensive exercise programme for patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis
2016
Abstract
This study demonstrated similar efficacy of exercise for both types of axial spondyloarthritis (axSpA), non -radiographic (nr)-axSpA and ankylosing spondylitis (AS). We found, for the first time, lowering of serum calprotectin levels in both types of axSpA after exercise training reflecting reduced disease activity and improved mobility.
Calprotectin levels may be a valuable biomarker of axSpA improvement, in particular in patients with nr-axSpA and axSpA patients without elevated C-reactive protein levels.