Abstract
Object: Description of the pregnancy in patient with anti-HPA-1a antibodies. Design: Case report.
Setting: Department of Obstetrics and Gynaecology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital. Case report: Report of cases of neonatal alloimune thrombocytopenia in a patient with proven anti-HPA 1a antibodies.
The immunization developed during the first pregnancy, accompanied with fetal thrombocytopenia which recurred in every subsequent pregnancy with greater severity. None of the neonates was affected by intracranial hemorrhage.