Charles Explorer logo
🇬🇧

Diabetes and dementia - what is known about their relationship?

Publication at Second Faculty of Medicine |
2016

Abstract

The prevalence of these two diseases is increasing. Diabetes, as well as dementia, homogeneous disease.

All forms of diabetes, hyperglycemia is common. All dementias connects progressive cognitive deterioration.

Patients with type 2 diabetes have a significantly higher risk of developing dementia than a person of the same age and sex who has normal glucose homeostasis. Is there a link? The article focuses on the function of insulin in the brain, the effects on the central insulin resistance for our cognitive abilities and psyche and to search for additional molecular link between impaired glucose homeostasis and the development of dementia.

The situation is compared with the two most common forms of diabetes, ie. Diabetes type 1 and 2.

The relationship between diabetes and dementia is still far from clear, but it seems that an important common denominator of both diabetes and dementia is insulin resistance. On frequent form of dementia in diabetic patients is also certainly sign a diabetes-related vascular changes and severe hypoglycemia.

Due to the negative impact of both diseases in the affected individual and society is a theme that is needed to be vigorously pursued.